Gestational diabetes & diabetes in pregnancy
Adaptive Mobile Health Intervention to Reduce Excess Gestational Weight Gain: A Cluster-Randomized Clinical Trial
Primary result · Weekly rate of GWGResult — go to the resultMean between-group difference −0.03 kg/week 95% CI −0.05 to −0.01Authors' conclusion
This cluster-randomized trial found that an adaptive intervention leveraging technology effectively reduced the rate of GWG and total GWG among pregnant patients with overweight or obesity.
Study context
- Population
- Pregnant patients with a singleton pregnancy, prepregnancy body mass index (BMI) 25.0 to <40.0, receiving care within an integrated health system; 58 clinicians; mean (SD) age 33.4 (4.6) years, mean (SD) BMI 29.8 (3.8)58 clinicians
- Participants
- 1,265 patients
- Comparison
- Adaptive mobile health lifestyle intervention plus standard care vs standard care alone
- Interventionn = 677
- Standard caren = 588reference
- Primary endpoint
- Co-primary: weekly rate of GWG and total GWG (both continuous and categorized per IOM guidelines)
Methodological detailscluster-randomized, randomization at the clinician level
- Cluster-randomized
- Randomization at the clinician level
Primary result
Weekly rate of GWG
Mean between-group difference
−0.03 kg/week
95% CI −0.05 to −0.01
By group
Interventionvs Standard care
mean between-group difference −0.03 kg/week (95% CI −0.05 to −0.01)
As reported in the abstract
Further findings
Mean, kg
| Outcome | Intervention | Standard care | Mean between-group difference (kg) (95% CI) | |
|---|---|---|---|---|
| Total GWG (co-primary)Co-primary outcome | 9.7 (SD 6.2) | 10.6 (SD 6.2) | −0.87 (−1.40 to −0.34) | |
| −2−101Difference, kg (linear scale) |
| Outcome | Intervention | Standard care | RR (95% CI) | |
|---|---|---|---|---|
| Exceeded IOM guidelines for weekly rate of GWG (co-primary, categorized) | 51.9% | 60.2% | 0.86 (0.78–0.95) | |
| Gained below IOM guidelines for weekly rate of GWG | 21.8% | 17.2% | 1.27 (1.01–1.61) | |
| Exceeded IOM guidelines for total GWG (co-primary, categorized) | 44.1% | 51.2% | 0.87 (0.77–0.98) | |
| Gained below IOM guidelines for total GWG | 26.8% | 21.5% | 1.23 (1.04–1.45) | |
| 0.512Relative risk (log scale) |
Original publication
Adaptive Mobile Health Intervention to Reduce Excess Gestational Weight Gain: A Cluster-Randomized Clinical Trial. JAMA Netw Open. Published 1 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →