Gestational diabetes & diabetes in pregnancy
Postnatal glycaemic outcomes in women with high‐risk gestational diabetes: Identifying key predictors for early intervention
Authors' conclusion
Ethnicity-specific prediction models integrating antepartum OGTT and HbA1c predict postpartum dysglycaemia in a multiethnic Southeast Asian cohort. Using these predictive models, we could identify high-risk patients for early intervention.
Study context
- Population
- Women with high-risk GDM (diabetic-range glucose excursions on antepartum oral glucose tolerance test (OGTT), GDM diagnosed on early OGTT, or ≥20 units of insulin antepartum), multiethnic Asian cohort, March 2020–March 2024
- Participants
- 561 women
- Outcome
- Predictors of postpartum OGTT attendance and of postpartum dysglycaemia
Main finding
As reported in the abstract
- Returned for postpartum OGTT
- 58.7% (n = 329)
- Chinese ethnicity, OR
- 2.11 (1.14-3.89) (95% CI)
- Pre-pregnancy body mass index (BMI), OR
- 0.95 (0.90-0.99) (95% CI)
- First GDM, OR
- 2.34 (1.39-3.96) (95% CI)
- 2-h glucose threshold on antepartum OGTT, OR
- 0.87 (0.76-0.99) (95% CI)
Observational data: associations, not effects.
Further findings
Predictors of postpartum dysglycaemia
- Chinese vs Malay women, odds of persistent postpartum dysglycaemia
- 4.5
- Antenatal HbA1c ≥5.7% and elevated 2-h post-OGTT glucose significantly predict postpartum dysglycaemia independent of ethnicity
Original publication
Postnatal glycaemic outcomes in women with high‐risk gestational diabetes: Identifying key predictors for early intervention. Diabetes Obes Metab. Published 27 November 2024. doi:10.
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