Gestational diabetes & diabetes in pregnancy
Postpartum dysglycaemia after early gestational diabetes: Follow-up of women in the TOBOGM randomised controlled trial
Authors' conclusion
There is a high incidence of postpartum dysglycaemia among high-risk women with eGDM.
Study context
- Population
- High-risk women with early GDM (eGDM) diagnosed <20 weeks' gestation by WHO criteria, overt diabetes in pregnancy excluded; postpartum OGTT recommended at 6–12 weeks352 had postpartum OGTT
- Participants
- 793 women
- Primary endpoint
- Incidence of postpartum dysglycaemia
- Follow-up
- 6-12 weeks postpartum
Methodological detailsfollow-up sub-study
- Follow-up sub-study
Primary result
As reported in the abstract
Postpartum dysglycaemia
- Postpartum dysglycaemia
- 92 (26.1%)
- Diabetes
- 11 (3.1%)
- Impaired fasting glucose (IFG)
- 31 (8.8%)
- Impaired glucose tolerance (IGT)
- 39 (11.1%)
- Combined IFG/IGT
- 11 (3.1%)
Further findings
Predictors of postpartum dysglycaemia
- Higher 1 and 2-hour glucose on early pregnancy OGTT, previous GDM and greater gestational weight gain independently associated with postpartum dysglycaemia (logistic regression)
- Women with dysglycaemia more likely to have past GDM, lower BMI, more gestational weight gain
Baseline characteristics with vs without postpartum OGTT
- Similar
Original publication
Postpartum dysglycaemia after early gestational diabetes: Follow-up of women in the TOBOGM randomised controlled trial. Diabetes Res Clin Pract. Published 12 November 2024. doi:10.
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