Obesity

Percentage of maximum weight lost as an optimal parameter of weight regain after bariatric surgery in Chinese patients with diabetes

Obesity (Silver Spring)Published Retrospective cohort study

Authors' conclusion

Among Chinese patients with obesity and T2DM who underwent bariatric surgery, WR quantified as %MWL predicted 3-year postoperative glucose metabolism deterioration better than the alternatives; 20% MWL was the optimal cutoff point.

Study context

Population
Chinese patients with obesity and T2D who underwent bariatric surgery, followed up to 3 years
Participants
249 patients
Exposure
Measures of weight regain: %MWL vs weight change, BMI change, % of presurgery weight, % of nadir weight
Outcome
Discrimination (C-index) of weight regain (WR) measures for glucose metabolism deterioration (new antidiabetic medication or insulin use, or HbA1c rise ≥0.5% to ≥5.7%)
Follow-up
Up to 3 years

Main finding

As reported in the abstract

C-index for glucose metabolism deterioration · within 3 years

Optimal %MWL cutoff point

20%

Observational data: associations, not effects.

Original publication

Percentage of maximum weight lost as an optimal parameter of weight regain after bariatric surgery in Chinese patients with diabetes. Obesity (Silver Spring). Published 3 May 2023. doi:10.1002/oby.23764

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