Obesity

Associations of change in body fat percentage with baseline body composition and diabetes remission after bariatric surgery

Obesity (Silver Spring)Published Cohort study

Authors' conclusion

BFP changes determine DR after bariatric surgery, and baseline FFMI is crucial for BFP changes. A low initial BMI is associated with a smaller BFP reduction and greater FFMI loss after bariatric surgery.

Study context

Population
Patients with T2D who underwent RYGB; verified in an SG cohort of 311 patientsRYGB cohort
Participants
203 patients
Exposure
Diabetes remission (DR) vs non-remission after RYGB
Outcome
Role of BFP changes in DR and association of baseline body composition with its changes
Methodological detailsvalidation cohort, Body composition measured by gold-standard-derived predictive equation and MRI
  • Validation cohort
  • Body composition measured by gold-standard-derived predictive equation and MRI

Main finding

As reported in the abstract

DR vs non-remission: higher baseline fat-free mass index (FFMI) and the most significant changes in body fat percentage (BFP)
p < 0.001
FFMI the most significant baseline variable correlated with BFP changes (linear regression)
p < 0.001

Observational data: associations, not effects.

Further findings

Replication in SG cohort

Findings replicated in the SG cohort

Original publication

Associations of change in body fat percentage with baseline body composition and diabetes remission after bariatric surgery. Obesity (Silver Spring). Published 22 March 2024. doi:10.1002/oby.24003

Composed by AI from the published abstract and checked against it. How Briefs are made →

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