Associations of change in body fat percentage with baseline body composition and diabetes remission after bariatric surgery
Authors' conclusion
BFP changes determine DR after bariatric surgery, and baseline FFMI is crucial for BFP changes. A low initial BMI is associated with a smaller BFP reduction and greater FFMI loss after bariatric surgery.
Study context
- Population
- Patients with T2D who underwent RYGB; verified in an SG cohort of 311 patientsRYGB cohort
- Participants
- 203 patients
- Exposure
- Diabetes remission (DR) vs non-remission after RYGB
- Outcome
- Role of BFP changes in DR and association of baseline body composition with its changes
Methodological detailsvalidation cohort, Body composition measured by gold-standard-derived predictive equation and MRI
- Validation cohort
- Body composition measured by gold-standard-derived predictive equation and MRI
Main finding
As reported in the abstract
- DR vs non-remission: higher baseline fat-free mass index (FFMI) and the most significant changes in body fat percentage (BFP)
- p < 0.001
- FFMI the most significant baseline variable correlated with BFP changes (linear regression)
- p < 0.001
Observational data: associations, not effects.
Further findings
Replication in SG cohort
- Findings replicated in the SG cohort
Original publication
Associations of change in body fat percentage with baseline body composition and diabetes remission after bariatric surgery. Obesity (Silver Spring). Published 22 March 2024. doi:10. 1002/ oby. 24003
Composed by AI from the published abstract and checked against it. How Briefs are made →