Obesity paradox and stroke outcomes according to stroke subtype: a propensity score-matched analysis
Authors' conclusion
These findings suggest that the obesity paradox in ischemic stroke outcomes might differ according to the stroke subtype.
Study context
- Population
- Consecutive patients with ischemic stroke from a prospective institutional stroke database, March 2014–December 2021
- Participants
- 2,779 patients
- Exposure
- Body mass index (BMI) categories and 90-d functional outcome, by stroke subtype
- Outcome
- Unfavorable outcome (mRS ≥ 3) vs favorable (mRS = 0-2)
- Follow-up
- 90 d
Methodological detailspropensity score-matched, prospective institutional database, consecutive patients
- Propensity score-matched
- Prospective institutional database
- Consecutive patients
Main finding
As reported in the abstract
Unfavorable outcome (mRS ≥ 3) by BMI category, by stroke subtype
Adjusted odds ratio (95% CI)
Overweightvs Normal weightCardioembolism subtype
0.38(0.20–0.74)
Obesevs Normal weightCardioembolism subtype
0.40(0.21–0.76)
ObesitySmall vessel disease subtype
0.55(0.32–0.95)
Observational data: associations, not effects.
Further findings
Unfavorable outcome (modified Rankin Scale (mRS) ≥ 3), all patients with stroke · 90 d
| aOR (95% CI) | ||
|---|---|---|
| ObesityInversely associated · propensity score-matched analysis | 0.61 (0.46–0.80) | |
| 0.512Adjusted odds ratio (log scale) |
Original publication
Obesity paradox and stroke outcomes according to stroke subtype: a propensity score-matched analysis. Int J Obes (Lond). Published 3 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →