Overweight and obesity are associated with better survival inSTEMIpatients with diabetes
Authors' conclusion
A U-shaped association governs the relationship between BMI and mortality in STEMI patients with diabetes, with those having overweight and obesity experiencing better survival.
Study context
- Population
- Patients with T2D and ST-elevation Myocardial Infarction (STEMI), National Inpatient Sample, 2008–2017
- Participants
- 74,099 patients
- Exposure
- BMI categories: underweight, overweight, obesity, severe obesity vs normal weight
- Outcome
- In-hospital outcomes (mortality) by BMI category
- Follow-up
- In-hospital
Methodological detailsNational Inpatient Sample 2008–2017
- National Inpatient Sample 2008–2017
Main finding
As reported in the abstract
In-hospital mortality, all years combined
Each group vs normal weightAdjusted odds ratio (95% CI)
Overweight
0.625(0.499–0.784)
Obesity
0.606(0.502–0.733)
Observational data: associations, not effects.
Further findings
BMI distribution over time · 2008 and 2017
- Obesity in 2008
- 35.8%
- Severe obesity in 2008
- 37.3%
- Obesity in 2017
- 57.8%
Temporal trend in mortality · 2008 to 2017
- Mortality decreased in underweight patients from 18.1% to 13.2%
- P < 0.001
- Mortality gradually increased in all other BMI ranges, along with cardiogenic shock, AF and ventricular fibrillation
- P < 0.001 for all
Original publication
Overweight and obesity are associated with better survival inSTEMIpatients with diabetes. Obesity (Silver Spring). Published 10 September 2023. doi:10. 1002/ oby. 23863
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