Diabetes complications

Overweight and obesity are associated with better survival inSTEMIpatients with diabetes

Obesity (Silver Spring)Published Retrospective cohort study

Authors' conclusion

A U-shaped association governs the relationship between BMI and mortality in STEMI patients with diabetes, with those having overweight and obesity experiencing better survival.

Study context

Population
Patients with T2D and ST-elevation Myocardial Infarction (STEMI), National Inpatient Sample, 2008–2017
Participants
74,099 patients
Exposure
BMI categories: underweight, overweight, obesity, severe obesity vs normal weight
Outcome
In-hospital outcomes (mortality) by BMI category
Follow-up
In-hospital
Methodological detailsNational Inpatient Sample 2008–2017
  • National Inpatient Sample 2008–2017

Main finding

As reported in the abstract

In-hospital mortality, all years combined
Lower mortality
Each group vs normal weightAdjusted odds ratio (95% CI)
Overweight
0.625(0.499–0.784)
Obesity
0.606(0.502–0.733)

Observational data: associations, not effects.

Further findings

BMI distribution over time · 2008 and 2017

Obesity in 2008
35.8%
Severe obesity in 2008
37.3%
Obesity in 2017
57.8%

Temporal trend in mortality · 2008 to 2017

Mortality decreased in underweight patients from 18.1% to 13.2%
P < 0.001
Mortality gradually increased in all other BMI ranges, along with cardiogenic shock, AF and ventricular fibrillation
P < 0.001 for all

Original publication

Overweight and obesity are associated with better survival inSTEMIpatients with diabetes. Obesity (Silver Spring). Published 10 September 2023. doi:10.1002/oby.23863

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.