Diabetes complications

An observational study of therapeutic procedures and in-hospital outcomes among patients admitted for acute myocardial infarction in Spain, 2016–2022: the role of diabetes mellitus

Cardiovasc DiabetolPublished Retrospective observational study

Main finding · IHMResult — go to the resultOdds ratio 1.06 95% CI 1.01–1.11

Authors' conclusion

PCI and CABG were associated with lower IHM in people admitted for STEMI/NSTEMI. Type 2-DM was associated with IHM in STEMI.

Study context

Population
Patients aged ≥ 18 years admitted for ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) in Spain, 2016–2022201,950 STEMIs
Exposure
Diabetes mellitus (DM) status in STEMI and NSTEMI
Outcome
In-hospital mortality (IHM)
Methodological detailsSpanish national hospital discharge data, logistic regression
  • Spanish national hospital discharge data
  • Logistic regression

Main finding

IHM

Odds ratio

1.06

95% CI 1.01–1.11

Type 2-DMvs Non-diabetic
OR 1.06 (95% CI 1.01–1.11)

As reported in the abstract

Lower in-hospital mortality (IHM) with percutaneous coronary intervention (PCI) in STEMI, OR
0.34 [0.32-0.35]
Lower IHM with PCI in NSTEMI, OR
0.24 [0.23-0.26]
Lower IHM with CABG in STEMI, OR
0.33 [0.27-0.40]
Lower IHM with CABG in NSTEMI, OR
0.45 [0.38-0.53]
IHM decreased over time in STEMI, OR
0.86 [0.80-0.93]

Observational data: associations, not effects.

Further findings

PCI frequency in STEMI (increase over time)

Non-diabetic
60.4% vs. 68.6%; p < 0.001
Type 2-DM
53.6% vs. 66.1%; p < 0.001

PCI frequency in NSTEMI (increase over time)

Non-diabetic
43.7% vs. 45.7%; p < 0.001
Type 2-DM
39.1% vs. 42.8%; p < 0.001

CABG frequency in NSTEMI (increase over time)

Non-diabetic
2.8% vs. 3.5%; p < 0.001
Type 2-DM
3.7% vs. 5.0%; p < 0.001

Original publication

An observational study of therapeutic procedures and in-hospital outcomes among patients admitted for acute myocardial infarction in Spain, 2016–2022: the role of diabetes mellitus. Cardiovasc Diabetol. Published 24 August 2024. doi:10.1186/s12933-024-02403-y

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