An observational study of therapeutic procedures and in-hospital outcomes among patients admitted for acute myocardial infarction in Spain, 2016–2022: the role of diabetes mellitus
Main finding · IHMResult — go to the resultOdds ratio 1.06 95% CI 1.01–1.11Authors' conclusion
PCI and CABG were associated with lower IHM in people admitted for STEMI/NSTEMI. Type 2-DM was associated with IHM in STEMI.
Study context
- Population
- Patients aged ≥ 18 years admitted for ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) in Spain, 2016–2022201,950 STEMIs
- Exposure
- Diabetes mellitus (DM) status in STEMI and NSTEMI
- Outcome
- In-hospital mortality (IHM)
Methodological detailsSpanish national hospital discharge data, logistic regression
- Spanish national hospital discharge data
- Logistic regression
Main finding
IHM
Odds ratio
1.06
95% CI 1.01–1.11
Type 2-DMvs Non-diabetic
OR 1.06 (95% CI 1.01–1.11)
As reported in the abstract
- Lower in-hospital mortality (IHM) with percutaneous coronary intervention (PCI) in STEMI, OR
- 0.34 [0.32-0.35]
- Lower IHM with PCI in NSTEMI, OR
- 0.24 [0.23-0.26]
- Lower IHM with CABG in STEMI, OR
- 0.33 [0.27-0.40]
- Lower IHM with CABG in NSTEMI, OR
- 0.45 [0.38-0.53]
- IHM decreased over time in STEMI, OR
- 0.86 [0.80-0.93]
Observational data: associations, not effects.
Further findings
PCI frequency in STEMI (increase over time)
- Non-diabetic
- 60.4% vs. 68.6%; p < 0.001
- Type 2-DM
- 53.6% vs. 66.1%; p < 0.001
PCI frequency in NSTEMI (increase over time)
- Non-diabetic
- 43.7% vs. 45.7%; p < 0.001
- Type 2-DM
- 39.1% vs. 42.8%; p < 0.001
CABG frequency in NSTEMI (increase over time)
- Non-diabetic
- 2.8% vs. 3.5%; p < 0.001
- Type 2-DM
- 3.7% vs. 5.0%; p < 0.001
Original publication
An observational study of therapeutic procedures and in-hospital outcomes among patients admitted for acute myocardial infarction in Spain, 2016–2022: the role of diabetes mellitus. Cardiovasc Diabetol. Published 24 August 2024. doi:10. 1186/ s12933-024-02403-y
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