Non‐alcohol substance use disorder after bariatric surgery in the prospective, controlled Swedish Obese Subjects study
Main finding · Non-alcohol SUD incidence per 1000 person-yearsResult — go to the resultAdjusted hazard ratio 2.54 95% CI 1.14–5.65Authors' conclusion
Gastric bypass surgery was associated with increased risk of non-alcohol SUD, and this should be considered in long-term postoperative care.
Study context
- Population
- Patients with obesity in the Swedish Obese Subjects study; those with history of non-alcohol substance use disorder (SUD) excluded2,010 surgery, 2037 controls
- Participants
- 265 / 1,369 / 376 / 2,037
- Exposure
- Bariatric surgery vs usual obesity care
- Gastric bypassn = 265
- Vertical banded gastroplastyn = 1,369
- Gastric bandingn = 376
- Controln = 2,037reference
- Outcome
- Incident non-alcohol substance use disorder (SUD), identified by ICD codes in the Swedish National Patient Register (hospital, not primary care)
- Follow-up
- Median 23.8 years
Methodological detailsmatched controls
- Matched controls
Main finding
Non-alcohol SUD incidence per 1000 person-years
Adjusted hazard ratio
2.54
95% CI 1.14–5.65
P = 0.022
By group
Gastric bypassvs Control
aHR 2.54 (95% CI 1.14–5.65); P = 0.022
As reported in the abstract
Observational data: associations, not effects.
Original publication
Non‐alcohol substance use disorder after bariatric surgery in the prospective, controlled Swedish Obese Subjects study. Obesity (Silver Spring). Published 21 July 2023. doi:10.
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