Life expectancy after bariatric surgery or usual care in patients with or without baseline type 2 diabetes in Swedish Obese Subjects
Authors' conclusion
Bariatric surgery is associated with similar reduction of overall and cardiovascular mortality and increased life expectancy regardless of baseline diabetes status.
Study context
- Population
- Patients with obesity with or without baseline T2D, Swedish Obese Subjects study; T2D: 392 surgery/305 controls; non-T2D: 1609 surgery/1726 controlsmatched cohort
- Participants
- 2,010 vs 2,037
- Exposure
- Bariatric surgery vs usual obesity care
- Surgeryn = 2,010
- Controln = 2,037reference
- Outcome
- Life expectancy and causes of death in relation to baseline T2D
- Follow-up
- Median 26 years
Methodological detailssubgroup analysis of the Swedish Obese Subjects study, matched controls, subgroup analysis by baseline T2D
- Subgroup analysis of the Swedish Obese Subjects study
- Matched controls
- Subgroup analysis by baseline T2D
Main finding
As reported in the abstract
Surgery vs ControlEstimate (95% CI)
T2D subgroup
increase in life expectancy, T2D 2.1 years(0.2–4.0)
non-T2D subgroup
increase in life expectancy, non-T2D 1.6 years(0.5–2.7)
Surgery vs ControlEstimate (95% CI)P value
T2D subgroup
aHR overall mortality, T2D 0.77(0.61–0.97)
non-T2D subgroup; treatment benefit similar
aHR overall mortality, non-T2D 0.82(0.72–0.94)
interaction p = 0.615Observational data: associations, not effects.
Further findings
| Outcome | Estimate | P value | |
|---|---|---|---|
| Cardiovascular mortality by baseline T2D statusSurgeryvs ControlT2D subgroup | aHR, T2D 0.65 (95% CI 0.46–0.91) | ||
| Cardiovascular mortality by baseline T2D statusSurgeryvs Controlnon-T2D subgroup | aHR, non-T2D 0.70 (95% CI 0.55–0.88) | interaction p = 0.516 | |
| 0.512Ratio (log scale) |
Original publication
Life expectancy after bariatric surgery or usual care in patients with or without baseline type 2 diabetes in Swedish Obese Subjects. Int J Obes (Lond). Published 12 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →