Obesity

Fast‐food environments and BMI changes in the Dutch adult general population: the Lifelines cohort

Obesity (Silver Spring)Published Population-based cohort study

Authors' conclusion

Fast-food outlet exposure was identified as a potentially important determinant of BMI and BMI change. Young adults, especially those with a medium or high genetic predisposition, had a higher BMI when exposed to fast-food outlets.

Study context

Population
Dutch adult general population, Lifelines cohort; residential addresses geocoded to fast-food outlet register (LISA); BMI measured objectively103,050 at follow-up
Participants
141,973 participants
Exposure
Fast-food outlets within 1 km of residence vs none
Outcome
BMI (cross-sectional) and BMI change (longitudinal)
Follow-up
baseline and 4-year follow-up
Methodological detailscross-sectional and longitudinal analyses, multivariable multilevel linear regression, exposure-moderator interactions
  • Cross-sectional and longitudinal analyses
  • Multivariable multilevel linear regression
  • Exposure-moderator interactions

Main finding

As reported in the abstract

BMI and BMI change

B

0.17

95% CI 0.09–0.25

≥1 fast-food outlet within 1 km · baseline BMI; higher with ≥1 outlet

B

0.06

95% CI 0.02–0.09

≥2 fast-food outlets within 1 km · BMI change; greater increase with ≥2 outlets

Observational data: associations, not effects.

Further findings

Baseline BMI, young adults (age 18-29 years)

Effect of fast-food outlet exposure on baseline BMI, young adults
0.35 [0.10 to 0.59] (B [95% CI])
Young adults with medium BMI genetic risk score
0.57 [−0.02 to 1.16] (B [95% CI])
Young adults with high BMI genetic risk score
0.46 [−0.24 to 1.16] (B [95% CI])
  • Genetic subsample: BMI n = 44,996; BMI change n = 36,684

Original publication

Fast‐food environments and BMI changes in the Dutch adult general population: the Lifelines cohort. Obesity (Silver Spring). Published 11 July 2023. doi:10.1002/oby.23781

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