Fifteen-year changes in health-related quality of life after bariatric surgery and non-surgical obesity treatment
Authors' conclusion
Over 15 years, surgical patients experienced more positive development of HRQoL compared to those receiving usual care. This difference was large for obesity-related problems, but otherwise the differences were small. Patients with pre-operative diabetes might be at increased risk for smaller long-term HRQoL improvements.
Study context
- Population
- Participants of the Swedish Obese Subjects study, recruited 1987–2001
- Participants
- 2,007 vs 2,040
- Exposure
- Bariatric surgery vs usual obesity care
- Surgeryn = 2,007
- Controlsn = 2,040reference
- Outcome
- Changes in mental, physical, social and obesity-related HRQoL (six HRQoL scales)
- Follow-up
- 15 years
Methodological detailsSwedish Obese Subjects study, non-randomized, matched controls, per-protocol, multilevel mixed-effect regression models, Measurements before treatment and after 0.5, 1, 2, 3, 4, 6, 8, 10 and 15 years
- Swedish Obese Subjects study
- Non-randomized
- Matched controls
- Per-protocol
- Multilevel mixed-effect regression models
- Measurements before treatment and after 0.5, 1, 2, 3, 4, 6, 8, 10 and 15 years
Main finding
As reported in the abstract
15-year HRQoL changes
Effect size large only for obesity-related problems
ES = 0.82
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| HRQoL at 15-year follow-up · 15 yearsSurgery vs Controls · better perceived health with surgery | P < 0.001 |
| HRQoL at 15-year follow-up · 15 yearsSurgery vs Controls · less obesity-related problems with surgery | P = 0.020 |
| 15-year HRQoL changes in surgery group by baseline diabetes · 15 yearsBaseline diabetes vs No baseline diabetes | P < 0.001 |
| 15-year HRQoL changes in surgery group by baseline diabetes · 15 yearsBaseline diabetes vs No baseline diabetes · smaller reduction in depression with baseline diabetes | P = 0.049 |
| 15-year HRQoL changes in surgery group by history of psychiatric disorder · 15 yearsPsychiatric history vs No psychiatric history · no significant differences in long-term improvements | P = 0.211-0.902 |
- 15-year health-related quality of life (HRQoL) changes in surgery group by baseline diabetes: smaller reduction in social interaction limitations with baseline diabetes
15-year HRQoL changes in surgery group by history of psychiatric disorder
- Lower HRQoL over follow-up with psychiatric history
Original publication
Fifteen-year changes in health-related quality of life after bariatric surgery and non-surgical obesity treatment. Int J Obes (Lond). Published 20 June 2024. doi:10.
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