Obesity

Metrics that matter: Identifying endpoints for capturing the broad health impacts of prevention of obesity

Diabetes Obes MetabPublished Targeted literature review

Authors' conclusion

We developed a novel framework that shortlisted five key cardiometabolic outcome measures for assessing obesity primary prevention benefits, with potential applications in health economic modelling and public health.

Study context

Population
Existing individual and composite metrics for prevention in adults, agnostic of disease or risk factor74 endpoints identified
Outcome
Cardiometabolic endpoints identified and shortlisted
Methodological detailssemi-structured expert review
  • Semi-structured expert review

Main finding

As reported in the abstract

Cardiometabolic endpoints identified
74
Holistic composites
7
User-centred composites
16
Health-based composites
31
Single clinical endpoints
20
Endpoints shortlisted: waist-to-height ratio, LDL-C, systolic and diastolic blood pressure, blood glucose, SF-12
5

Original publication

Metrics that matter: Identifying endpoints for capturing the broad health impacts of prevention of obesity. Diabetes Obes Metab. Published 25 August 2025. doi:10.1111/dom.70016

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