A Randomised Controlled Trial Testing a Behavioural Intervention Program for the Prevention of Type 2 Diabetes Among American Indian Youth: The Tribal Turning Point Study
Authors' conclusion
In this trial among American Indian youth spanning the COVID-19 pandemic, the TTP intervention yielded short-term improvements on obesity measures but only in the subset who participated before the pandemic.
Study context
- Population
- American Indian youth (7–10 years) with overweight/obesity, 2018–2023
- Participants
- 87 vs 95
- Comparison
- Tribal turning point behavioural intervention vs control
- Tribal turning point (TTP)n = 87
- Controln = 95reference
- Primary endpoint
- Co-primary: change in BMI and fasting insulin
- Follow-up
- 12 months
Primary result
As reported in the abstract
- No significant differences by randomization for either primary outcome
Further findings
| Outcome | P value |
|---|---|
| Change in age/sex-adjusted BMI z-score, subset completing 6-month assessments before COVID-19 pandemic · significantly decreased change with TTP | P = 0.028 |
| Change in waist circumference, subset completing 6-month assessments before COVID-19 pandemic · significantly decreased change with TTP | P = 0.040 |
Original publication
A Randomised Controlled Trial Testing a Behavioural Intervention Program for the Prevention of Type 2 Diabetes Among American Indian Youth: The Tribal Turning Point Study. Pediatr Obes. Published 30 August 2025. doi:10.
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