Implementing a Low-Calorie diet to Enhance weight loss in the diabetes Prevention Program during a humanitarian Crisis: A pilot pragmatic randomized trial in Venezuela
Authors' conclusion
Initiating the DPP with intensive low-calorie restriction led to greater weight loss and improved chances of meeting weight loss goals during a humanitarian crisis.
Study context
- Population
- Venezuelan adults with elevated risk of T2D during a humanitarian crisis, Community Health Center70 (55.1%) completed
- Participants
- 127 adults
- Comparison
- Low-calorie liquid diet followed by Diabetes Prevention Program (DPP) vs DPP
- LD-DPPn = 64
- DPPn = 63reference
- Primary endpoint
- Achievement of the 7% weight loss goal
- Follow-up
- Six months
Methodological detailspilot, pragmatic, single-centre, ITT and per-protocol analyses with inverse probability weighting
- Pilot
- Pragmatic
- Single-centre
- ITT and per-protocol analyses with inverse probability weighting
Primary result
As reported in the abstract
Achieved 7% weight loss goal
- Overall achieved 7% weight loss goal
- 32.9%
Original publication
Implementing a Low-Calorie diet to Enhance weight loss in the diabetes Prevention Program during a humanitarian Crisis: A pilot pragmatic randomized trial in Venezuela. Diabetes Res Clin Pract. Published 22 February 2025. doi:10. 1016/ j. diabres. 2025. 112051
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