Cumulative abdominal obesity exposure and progressive risk of endometrial cancer in young women: a nationwide cohort study
Authors' conclusion
In this population-based nationwide cohort study of young women, we observed a progressive increase in the risk of endometrial cancer with cumulative abdominal obesity exposure.
Study context
- Population
- Women aged 20–39 years with four consecutive annual health examinations 2009–2012 and no history of cancer at baseline, South Korea; mean (SD) age 30.82 (4.55) years302 developed endometrial cancer
- Participants
- 445,791 women
- Exposure
- Abdominal obesity exposure numbers 1–4 vs 0
- Outcome
- Newly diagnosed endometrial cancer
- Follow-up
- Monitored until 2020; 7.12 years
Methodological detailsSouth Korean National Health Insurance Service data
- South Korean National Health Insurance Service data
Main finding
As reported in the abstract
Incident endometrial cancer · follow-up 7.12 years
- Cumulative incidence differed significantly by number of abdominal obesity exposures (log-rank test)
- P < .001
- Developed endometrial cancer
- 302
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Cumulative abdominal obesity exposure and progressive risk of endometrial cancer in young women: a nationwide cohort study. Int J Obes (Lond). Published 22 August 2025. doi:10.
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