Metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes: risk of heart failure
Authors' conclusion
SLD is independent risk factor of new-onset HF and CV mortality in persons with T2DM, and alcohol consumption has a J-shaped association with risk of HF and CV mortality, regardless of SLD status.
Study context
- Population
- Adults with T2D, followed from 2009–2012 until 2018
- Participants
- 2,745,689 adults
- Exposure
- SLD categories vs no SLD
- Outcome
- Risk of HF and CV mortality
Main finding
As reported in the abstract
HF
aHR
- MASLD
- 1.11
- MetALD
- 1.14
- ALD with MD
- 1.32
- MASLD with viral hepatitis (VH)
- 1.12
Observational data: associations, not effects.
Further findings
Prevalence of SLD categories
Cardiovascular (CV) mortality
- Risk of CV mortality also increased in SLD groups vs no SLD
Alcohol consumption and new-onset heart failure (HF) and CV mortality
- J-shaped association with alcohol consumption regardless of SLD status
Original publication
Metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes: risk of heart failure. Cardiovasc Diabetol. Published 1 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →