Lipids & metabolic liver disease
Associations between steatotic liver disease subtypes and incident diabetes in young Korean adults: A nationwide cohort study
Authors' conclusion
All SLD subtypes significantly increased the risk of type 2 diabetes in young adults, with the greatest risk in ALD, followed by MetALD and MASLD. Early detection and management of SLD are essential to reduce the future burden of diabetes.
Study context
- Population
- Korean adults aged 20–39 who underwent health examinations between 2009 and 2012; Steatotic liver disease (SLD) subtypes classified by fatty liver index and alcohol intake72,028 developed T2D
- Participants
- 6,250,145 adults
- Exposure
- SLD subtypes vs non-SLD
- Outcome
- Incident T2D
- Follow-up
- Median 10.6 years
Methodological detailsKorean National Health Insurance Service database, Cox proportional hazards models
- Korean National Health Insurance Service database
- Cox proportional hazards models
Main finding
As reported in the abstract
Each group vs non-SLDAdjusted hazard ratio (95% CI)
MASLD
2.81(2.78–2.85)
MetALD
2.92(2.87–2.98)
ALD
3.99(3.88–4.09)
Observational data: associations, not effects.
Original publication
Associations between steatotic liver disease subtypes and incident diabetes in young Korean adults: A nationwide cohort study. Diabetes Obes Metab. Published 15 December 2025. doi:10. 1111/ dom. 70381
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