Lipids & metabolic liver disease

Associations between steatotic liver disease subtypes and incident diabetes in young Korean adults: A nationwide cohort study

Diabetes Obes MetabPublished Nationwide cohort study

Authors' conclusion

All SLD subtypes significantly increased the risk of type 2 diabetes in young adults, with the greatest risk in ALD, followed by MetALD and MASLD. Early detection and management of SLD are essential to reduce the future burden of diabetes.

Study context

Population
Korean adults aged 20–39 who underwent health examinations between 2009 and 2012; Steatotic liver disease (SLD) subtypes classified by fatty liver index and alcohol intake72,028 developed T2D
Participants
6,250,145 adults
Exposure
SLD subtypes vs non-SLD
Outcome
Incident T2D
Follow-up
Median 10.6 years
Methodological detailsKorean National Health Insurance Service database, Cox proportional hazards models
  • Korean National Health Insurance Service database
  • Cox proportional hazards models

Main finding

As reported in the abstract

Each group vs non-SLDAdjusted hazard ratio (95% CI)
MASLD
2.81(2.78–2.85)
MetALD
2.92(2.87–2.98)
ALD
3.99(3.88–4.09)

Observational data: associations, not effects.

Original publication

Associations between steatotic liver disease subtypes and incident diabetes in young Korean adults: A nationwide cohort study. Diabetes Obes Metab. Published 15 December 2025. doi:10.1111/dom.70381

Composed by AI from the published abstract and checked against it. How Briefs are made →

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