Short- and long-term mortality in patients with type 2 diabetes after myocardial infarction– a nationwide registry study
Main finding · MortalityResult — go to the resultHazard ratio 1.20 95% CI 1.17–1.24Authors' conclusion
Type 2 diabetes had a negative impact on both short- and long-term outcome after MI, but effect sizes were relatively small. Patients with longer duration of diabetes or need for insulin therapy are still at particular risk.
Study context
- Population
- Consecutive myocardial infarction (MI) patients treated in Finland 2004–2018; T2D: 40% female, mean age 73.6 yearspropensity score-matched
- Participants
- 13,152 vs 77,669
- Exposure
- T2D vs no diabetes after MI
- T2Dn = 13,152
- No diabetesn = 77,669reference
- Outcome
- Mortality
- Follow-up
- 30 days, 1 year and 15 years after MI (median 5.7 years)
Methodological detailspropensity score matching, multivariable adjustment, national registries
- Propensity score matching
- Multivariable adjustment
- National registries
Main finding
As reported in the abstract
15 years
Hazard ratio
1.20
95% CI 1.17–1.24
P < 0.0001
By group
T2Dvs No diabetes
HR 1.20 (95% CI 1.17–1.24); P < 0.0001
Observational data: associations, not effects.
Further findings
Mortality · 30 days · propensity score-matched controls
P = 0.013
Mortality · 1 year · propensity score-matched controls
P = 0.001
Subgroups and predictors of mortality in T2D
- T2D associated with poorer prognosis across the spectrum of MI patients
- Excess mortality risk attenuated by increasing age; similar in both sexes
- Male sex, age, CV and non-CV comorbidities, lack of revascularization, longer diabetes duration and baseline insulin therapy associated with increased mortality in T2D
- 1-year prognosis in T2D improved over study period; mortality gap vs no diabetes not altered
Original publication
Short- and long-term mortality in patients with type 2 diabetes after myocardial infarction– a nationwide registry study. Cardiovasc Diabetol. Published 30 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →