Prescription Fills Among Patients With Type 2 Diabetes After Hospitalization for Acute Coronary Syndrome
Authors' conclusion
In this cohort study of Medicare beneficiaries with T2D, longer-term medication use following hospitalization for MI was associated with medication use at the time of discharge. These findings highlight the critical importance of this period to optimize preventive care for these high-risk individuals. Further implementation science research is needed to develop strategies to improve use of these evidence-based medications.
Study context
- Population
- Medicare beneficiaries older than 18 years with T2D hospitalized for myocardial infarction (MI) or coronary revascularization, CMS data January 1, 2018, to June 30, 2020; median age 73.0 years, 59.4% men
- Participants
- 188,651 participants
- Exposure
- Not filling vs filling a cardiovascular medication at discharge
- Outcome
- Lack of Medicare Part D prescription fills of evidence-based agents (angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blockers (ARBs)/angiotensin receptor-neprilysin inhibitors (ARNIs); β-blockers; P2Y12Is; statins/PCSK9Is; GLP-1 RA/SGLT2i) in the postdischarge period
- Follow-up
- 91-180 days after discharge
Main finding
As reported in the abstract
Not filling cardiovascular medication after hospitalization
Estimate (95% CI)
Not filled at dischargevs Filled at discharge
adjusted risk ratio (ACEIs, ARBs, or ARNIs) 0.27(0.27–0.28)
Not filled at dischargevs Filled at discharge
adjusted risk ratio (β-blockers) 0.24(0.24–0.25)
Not filled at dischargevs Filled at discharge
adjusted risk ratio (P2Y12Is) 0.20(0.19–0.20)
Not filled at dischargevs Filled at discharge
adjusted risk ratio (statins or PCSK9Is) 0.31(0.31–0.32)
Not filled at dischargevs Filled at discharge
adjusted risk ratio (SGLT2Is or GLP-1RAs) 0.27(0.26–0.28)
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Prescription Fills Among Patients With Type 2 Diabetes After Hospitalization for Acute Coronary Syndrome. JAMA Netw Open. Published 4 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →