Gestational diabetes & diabetes in pregnancy
Mean Glucose and Gestational Weight Gain as Predictors of Large-for-Gestational-Age Infants in Pregnant Women with Type 1 Diabetes Using Continuous Glucose Monitoring
Main finding · Mean glucoseResult — go to the resultDifference 0.4 mmol/LAuthors' conclusion
Women with T1D delivering LGA infants achieved glycemic targets later than women delivering AGA infants. Mean glucose and gestational weight gain were independent predictors for delivering LGA infants. Infants born LGA remained larger postdelivery compared with infants born AGA.
Study context
- Population
- Pregnant women with T1D using isCGM from conception until delivery
- Participants
- 111 women
- Exposure
- Women delivering large-for-gestational-age (LGA) vs appropriate-for-gestational-age (AGA) infants
- LGAn = 59
- Outcome
- Glycemic metrics during pregnancy (mean glucose, TIRp, time above/below range, CV) compared between women delivering LGA and AGA infants; predictors of LGA infants
Main finding
Mean glucose · 11-33 weeks
Difference
0.4 mmol/L
P = 0.01
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | LGA | AGA | P value |
|---|---|---|---|
| Infant weight · 3 months postdeliveryHigher in infants born LGA | 6360 ± 784 g | 5988 ± 894 | P = 0.04 |
Original publication
Mean Glucose and Gestational Weight Gain as Predictors of Large-for-Gestational-Age Infants in Pregnant Women with Type 1 Diabetes Using Continuous Glucose Monitoring. Diabetes Technol Ther. Published 22 April 2024. doi:10. 1089/ dia. 2023. 0583
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