Gestational diabetes & diabetes in pregnancy
Maternal gestational diabetes and childhood adiposity risk from 6 to 8 years of age
Authors' conclusion
Maternal GDM was a risk factor of childhood overweight/obesity at both 5.9 and 8.3 years of age, which was independent from several important confounders including maternal pre-pregnancy BMI, gestational weight gain, children's birth weight and lifestyle factors. This significant and positive association became stronger with age.
Study context
- Population
- Mother-child pairs followed at 5.9 ± 1.2 and 8.3 ± 1.6 years postpartum912 retained at 8.3 years
- Participants
- 1,156 pairs
- Exposure
- Children of mothers with gestational diabetes mellitus (GDM) vs without GDM
- GDMn = 578
- Non-GDMn = 578reference
- Outcome
- Offspring adiposity risk (BMI, waist circumference, body fat, skinfold)
- Follow-up
- 6 to 8 years of age
Main finding
As reported in the abstract
Change in childhood adiposity indicators associated with maternal GDM · 5.9-year to 8.3-year visit
- GDM
- β (z score of body mass index (BMI) for age) +0.10 (95% CI 0.02–0.18)
- GDM
- β (waist circumference) +1.46 cm (95% CI 0.70–2.22)
- GDM
- β (body fat) +1.78% (95% CI 1.16%–2.40%)
- GDM
- β (triceps skinfold) +2.40 mm (95% CI 1.78–3.01)
- GDM
- β (subscapular skinfold) +1.59 mm (95% CI 1.10–2.09)
- GDM
- β (suprailiac skinfold) +2.03 mm (95% CI 1.35–2.71)
Observational data: associations, not effects.
Further findings
Childhood overweight/obesity, central obesity and high body fat · 5.9 and 8.3 years
- OR range at 5.9 years, GDM vs non-GDM
- 1.41-1.57
- OR range at 8.3 years, GDM vs non-GDM
- 1.73-2.03
Original publication
Maternal gestational diabetes and childhood adiposity risk from 6 to 8 years of age. Int J Obes (Lond). Published 20 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →