Maternal and parental anxiety levels before and after the child’s seroconversion to islet autoimmunity
Authors' conclusion
Type 1 diabetes related anxiety is common among parents participating in genetic screening at birth and receiving information on high genetic risk after screening at birth, declining over time. Information on islet autoantibody positivity increases type 1 diabetes related anxiety. Having a first degree relative and being a mother increase the risk of anxiety, while fathers and parents satisfied with participation are less anxious.
Study context
- Population
- Parents of children screened at birth for genetic risk of T1D and enrolled at 4–7 months in the Primary Oral Insulin Trial (POInT) study
- Exposure
- Mothers vs Fathers
- Outcome
- Parental T1D-related anxiety, State Anxiety Inventory (SAI)
- Follow-up
- 8-11, 18 and 36 months of age
Methodological detailsnested in the POInT prevention study
- Nested in the POInT prevention study
Main finding
As reported in the abstract
High T1D-related anxiety · child aged 8-11 months
Observational data: associations, not effects.
Further findings
Factors associated with anxiety (linear regression) · all time-points
- Anxiety associated with country of residence, first degree relative with T1D and parental study satisfaction, for mothers and fathers
- First degree relatives more anxious than general population
- Parents more satisfied with study participation less anxious
- Parents from Poland and Belgium more anxious than from Germany and Sweden
Original publication
Maternal and parental anxiety levels before and after the child’s seroconversion to islet autoimmunity. Horm Res Paediatr. Published 30 September 2026. doi:10.
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