Lipids & metabolic liver disease
Magnesium Depletion Score and Metabolic Syndrome in US Adults: Analysis of National Health and Nutrition Examination Survey (NHANES) 2003 to 2018
Authors' conclusion
Higher urinary magnesium loss as quantified by MDS may be an independent linear risk factor for MetS in US adults, irrespective of sociodemographic and behavioral factors. Optimizing magnesium nutritional status could potentially confer benefits to patients with MetS.
Study context
- Population
- US adults in NHANES 2003 to 2018; Metabolic syndrome (MetS) defined by NCEP ATP III
- Participants
- 15,565 adults
- Exposure
- Per-unit increase in magnesium depletion score
- Outcome
- Metabolic syndrome (MetS)
Methodological detailsNHANES 2003 to 2018, weighted univariate and multivariable logistic regression, restricted cubic spline analysis, stratified analyses
- NHANES 2003 to 2018
- Weighted univariate and multivariable logistic regression
- Restricted cubic spline analysis
- Stratified analyses
Main finding
As reported in the abstract
MetS per unit increase in MDS
OR per unit increase in magnesium depletion score (MDS), adjusted for confounding factors
1.31
95% CI 1.17–1.45
Observational data: associations, not effects.
Further findings
Subgroups by age, sex, race, adiposity, smoking status, alcohol consumption
- Positive correlation consistent across subgroups; no significant interaction
Original publication
Magnesium Depletion Score and Metabolic Syndrome in US Adults: Analysis of NHANES 2003 to 2018. J Clin Endocrinol Metab. Published 14 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →