Lipids & metabolic liver disease
Association of the triglyceride glucose index with all-cause and cardiovascular mortality in a general population of Iranian adults
Authors' conclusion
The predicting value of TyG index for ACM and CVM might be mediated by diabetes status. Further studies are required to confirm these findings.
Study context
- Population
- Iranian adults aged ≥35 years with no history of cardiovascular disease (CVD) events
- Participants
- 5,432 adults
- Exposure
- Tertiles of triglyceride glucose (TyG) index
- Outcome
- CVD mortality and all-cause mortality
- Follow-up
- Median 11.25 years
Methodological detailsCox frailty model for hazard ratios (HRs) across TyG index tertiles
- Cox frailty model for HRs across TyG index tertiles
Main finding
As reported in the abstract
Deaths recorded: CVD
191
Deaths recorded: all-cause
487
All-cause mortality risk increase, model adjusted for lifestyle and metabolic variables
41%
95% CI 1.11, 1.81P for trend = 0.005
CVD mortality risk increase, model adjusted for lifestyle and metabolic variables
64%
95% CI 1.07, 2.50P for trend = 0.024
Observational data: associations, not effects.
Further findings
Non-CVD mortality
- TyG was not related to the risk of non-CVD mortality
Sex differences
- Associations may vary by sex
Original publication
Association of the triglyceride glucose index with all-cause and cardiovascular mortality in a general population of Iranian adults. Cardiovasc Diabetol. Published 12 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →