Gestational diabetes & diabetes in pregnancy
Low Gestational Weight Gain in Women With Gestational Diabetes Is Safe With Better Metabolic Profile Postpartum
Authors' conclusion
GWG below IOM guidelines occurred frequently in GDM women, without increased risk for adverse pregnancy outcomes and with better metabolic profile postpartum. Excessive GWG was associated with increased risk for neonatal hypoglycemia and worse metabolic profile postpartum in women with GDM, and with higher rates of LGA and instrumental delivery in NGT women.
Study context
- Population
- Pregnant women receiving universal GDM screening with a 75-g OGTT, 7 Belgian hospitals
- Participants
- 1,843 women
- Exposure
- Gestational weight gain (GWG) below, within or above Institute of Medicine (IOM) guidelines in women with GDM and normal glucose tolerance (NGT)
- GDM low GWGn = 97
- GDM GWG within rangen = 58reference
- GDM excessive GWGn = 30
- NGT excessive GWGn = 383
- Outcome
- Pregnancy outcomes and postpartum characteristics
Methodological detailsmulticentre (7 Belgian hospitals), universal GDM screening with 75-g OGTT
- Multicentre (7 Belgian hospitals)
- Universal GDM screening with 75-g OGTT
Main finding
As reported in the abstract
Adjusted odds ratio (95% CI)P value
GDM excessive GWGvs GDM GWG within rangeNeonatal hypoglycemia: 30.8% (8) vs 5.9% [3]
7.15(1.52–33.63)
P = 0.013NGT excessive GWGvs NGT GWG within rangeInstrumental delivery: 15.9% [61] vs 11.9% [64]
1.53(1.03–2.27)
P = 0.035NGT excessive GWGvs NGT GWG within rangeLarge-for-gestational age infants: 19.3% [74] vs 10.4% [56]
1.67(1.13–2.47)
P = 0.012Observational data: associations, not effects.
Original publication
Low Gestational Weight Gain in Women With Gestational Diabetes Is Safe With Better Metabolic Profile Postpartum. J Clin Endocrinol Metab. Published 14 October 2022. doi:10.
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