Low Bacteroides abundance is related to endothelial dysfunction in type 2 diabetes
Authors' conclusion
Low Bacteroides abundance is associated with low RHI and may be associated with the risk of atherosclerosis in patients with T2D.
Study context
- Population
- Patients with T2D (68 men and 25 women)68 men · 25 women
- Participants
- 93 patients
- Exposure
- Low vs high relative Bacteroides abundance
- Outcome
- Association of relative Bacteroides abundance with endothelial function (reactive hyperemia index, RHI)
Main finding
As reported in the abstract
Natural log-transformed RHI (Ln-RHI)
- Ln-RHI positively correlated with Ln-relative Bacteroides abundance (p < 0.05)
- Low Bacteroides vs High Bacteroides: P = 0.038
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| High-sensitivity C-reactive proteinTended to be higher with Low Bacteroides | P = 0.069 |
Plasma acetate
- Plasma acetate correlated with relative Bacteroides abundance (p = 0.036) but not with Ln-RHI
Other bacteria
- No other bacterial differences between the groups were associated with the reactive hyperemia index (RHI)
Original publication
Low Bacteroides abundance is related to endothelial dysfunction in type 2 diabetes. Diabetes Res Clin Pract. Published 25 September 2025. doi:10.
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