Diabetes technology

Interpreting Glucose Management Indicator and Point-of-Care Hemoglobin A1c (A1c) Discrepancies in Pediatric Patients with Islet Autotransplantation and Hemoglobin A1c Under 6.5%: A Guide for TPIAT Providers

J Diabetes Sci TechnolPublished Retrospective cohort study

Authors' conclusion

Our data demonstrate a significant discordance between 14-day GMI and POC A1c values, particularly when A1c falls below 6.5%, in patients 1-year post-TPIAT.

Study context

Population
Pediatric patients 1-year post-TPIAT at Cincinnati Children's Hospital with point-of-care (POC) A1c and continuous glucose monitoring (CGM) data 12 months post-TPIAT59 records reviewed
Participants
33 patients
Exposure
Point-of-care A1c vs 14-day glucose management indicator (GMI)
Outcome
Agreement of POC A1c with 14-day GMI
Follow-up
1-year post-TPIAT
Methodological detailssingle-centre, medical record review
  • Single-centre
  • Medical record review

Main finding

As reported in the abstract

POC A1c vs 14-day GMI

P < 0.0001

Observational data: associations, not effects.

Further findings

GMI higher than POC A1c, by A1c stratum · 1-year post-TPIAT

P < 0.0001

Original publication

Interpreting Glucose Management Indicator and Point-of-Care Hemoglobin A1c Discrepancies in Pediatric Patients with Islet Autotransplantation and Hemoglobin A1c Under 6.5%: A Guide for TPIAT Providers. J Diabetes Sci Technol. Published 20 July 2026. doi:10.1177/19322968261465344

Composed by AI from the published abstract and checked against it. How Briefs are made →

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