Interpreting Glucose Management Indicator and Point-of-Care Hemoglobin A1c (A1c) Discrepancies in Pediatric Patients with Islet Autotransplantation and Hemoglobin A1c Under 6.5%: A Guide for TPIAT Providers
Authors' conclusion
Our data demonstrate a significant discordance between 14-day GMI and POC A1c values, particularly when A1c falls below 6.5%, in patients 1-year post-TPIAT.
Study context
- Population
- Pediatric patients 1-year post-TPIAT at Cincinnati Children's Hospital with point-of-care (POC) A1c and continuous glucose monitoring (CGM) data 12 months post-TPIAT59 records reviewed
- Participants
- 33 patients
- Exposure
- Point-of-care A1c vs 14-day glucose management indicator (GMI)
- Outcome
- Agreement of POC A1c with 14-day GMI
- Follow-up
- 1-year post-TPIAT
Methodological detailssingle-centre, medical record review
- Single-centre
- Medical record review
Main finding
As reported in the abstract
POC A1c vs 14-day GMI
P < 0.0001
Observational data: associations, not effects.
Further findings
GMI higher than POC A1c, by A1c stratum · 1-year post-TPIAT
P < 0.0001
Original publication
Interpreting Glucose Management Indicator and Point-of-Care Hemoglobin A1c Discrepancies in Pediatric Patients with Islet Autotransplantation and Hemoglobin A1c Under 6.5%: A Guide for TPIAT Providers. J Diabetes Sci Technol. Published 20 July 2026. doi:10. 1177/ 19322968261465344
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