Type 2 & other diabetes

International consensus recommendations for smoking cessation in type 2 diabetes from the DiaSmokeFree Working group

Diabetes Res Clin PractPublished International consensus recommendations

Methodological detailsmultidisciplinary panel, structured multi-stakeholder consensus process, GRADE where feasible, AGREE reporting framework, Panel of 35 experts from 13 countries
  • Multidisciplinary panel
  • Structured multi-stakeholder consensus process
  • GRADE where feasible
  • AGREE reporting framework
  • Panel of 35 experts from 13 countries

Recommendations

As issued by the authors

  1. Varenicline is the only medication that can be strongly recommended; evidence on pharmacological treatment in T2D is limited

  2. Intensive, individualized interventions combining pharmacotherapy, behavioral support and relapse management are more effective than brief interventions

  3. Drug-smoke interactions may require dose adjustments (e.g., drugs affected by CYP1A2, UGT enzymes or renal transporters)

  4. Smoking cessation substantially reduces the increased cardiovascular, stroke and macrovascular risk associated with smoking in T2D

Original publication

International consensus recommendations for smoking cessation in type 2 diabetes from the DiaSmokeFree Working group. Diabetes Res Clin Pract. Published 28 August 2026. doi:10.1016/j.diabres.2026.113528

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