Type 2 & other diabetes

Consensus Recommendations on Lipohypertrophy: Insights From an International Panel of Experts

Diabetes Res Clin PractPublished Consensus statement

Methodological detailsmodified Delphi methodology, international expert panel
  • Modified Delphi methodology
  • International expert panel

Recommendations

As issued by the authors

  1. Inadequate injection site rotation identified as the strongest modifiable risk factor for lipohypertrophy

  2. Systematic injection site examination every 6 months during the first 2 years of insulin therapy, then annually, with more frequent screening for high-risk people with diabetes (PwD)

  3. Standardized examination protocols with visual inspection and systematic palpation; US reserved for detecting subclinical lipohypertrophy

  4. Prevention: proper education, site rotation and single-use needle practices

Original publication

Consensus Recommendations on Lipohypertrophy: Insights From an International Panel of Experts. Diabetes Res Clin Pract. Published 3 July 2026. doi:10.1016/j.diabres.2026.113401

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