Increased glycemic variability in pregnant women with Roux-en-Y gastric bypass compared with sleeve gastrectomy
Authors' conclusion
Pregnant women who have undergone RYGB have greater GV during pregnancy compared with those who have undergone SG. Further research is needed to establish the relationship between GV and pregnancy outcomes to determine the preferred bariatric operation in women of reproductive age, and whether interventions to reduce GV might improve outcomes.
Study context
- Population
- Pregnant women after bariatric surgery, investigated with CGM in the second or third trimester
- Participants
- 14 vs 14
- Exposure
- RYGB vs sleeve gastrectomy (SG)
- RYGBn = 14
- SGn = 14reference
- Outcome
- GV during pregnancy
- Follow-up
- Second or third trimester
Methodological detailsroutine clinical care
- Routine clinical care
Main finding
As reported in the abstract
GV (CGM)
- Similar mean interstitial glucose with RYGB vs SG
- Significantly increased indices of glycemic variability (GV) with RYGB vs SG
- Lower %TIR 3.9-7.8 mmol/L (70-140 mg/dL) with RYGB vs SG
Observational data: associations, not effects.
Original publication
Increased glycemic variability in pregnant women with Roux-en-Y gastric bypass compared with sleeve gastrectomy. BMJ Open Diabetes Res Care. Published 17 January 2024. doi:10.
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