Incidence of Type 1 Diabetes in Relation to Exposure to Rotavirus Infections in Pre- and Postvaccine Birth Cohorts in Finland
Main finding · T1D incidence, age <5 yearsResult — go to the resultIncidence rate ratio 0.79 95% CI 0.71–0.86Authors' conclusion
At the population level, a decrease in exposure to rotavirus infections was associated with a decrease in the incidence of type 1 diabetes in young children.
Study context
- Population
- Children in the 1995–2015 birth cohorts in Finland
- Comparison
- Postvaccine vs prevaccine birth cohorts
- Outcome
- Incidence of T1D in children aged <5 years
Methodological detailsnationwide, register-based
- Nationwide
- Register-based
Main finding
T1D incidence, age <5 years
Incidence rate ratio
0.79
95% CI 0.71–0.86
By group
Postvaccine birth cohortsvs Prevaccine 2001-2005 birth cohorts
IRR 0.79 (95% CI 0.71–0.86)
As reported in the abstract
Further findings
| Outcome | Postvaccine birth cohorts | Prevaccine 2001-2005 birth cohorts |
|---|---|---|
| Children exposed to rotavirus infection by age 5 years | 171 per 100,000 children (0.2%) | 2,522 per 100,000 children (2.5%) |
Original publication
Incidence of Type 1 Diabetes in Relation to Exposure to Rotavirus Infections in Pre- and Postvaccine Birth Cohorts in Finland. Diabetes Care. Published 20 October 2023. doi:10.
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