Gestational diabetes & diabetes in pregnancy
Impact of different types of hypertensive disorders of pregnancy and their duration on incident post-partum risk of diabetes mellitus: Results from the French nationwide study CONCEPTION
Authors' conclusion
Women who experienced an HDP had twice the risk of developing DM. Early blood glucose assessment and blood pressure monitoring should be more widely recommended after HDP diagnosis.
Study context
- Population
- Primiparous women in the French CONCEPTION cohort who delivered between 2010 and 2018; follow-up to 31 December 2021
- Participants
- 2,816,793 women
- Exposure
- Hypertensive disorders of pregnancy (HDP) types vs no HDP
- Outcome
- Incident DM
- Follow-up
- Mean 4.5 years
Methodological detailsnationwide, Cox models; HDP and DM identified by ICD-10 hospital diagnoses and/or medication dispensing
- Nationwide
- Cox models; HDP and DM identified by ICD-10 hospital diagnoses and/or medication dispensing
Main finding
As reported in the abstract
Incident DM, women without gestational diabetes
Each group vs no HDPAdjusted hazard ratio (CI)
GH
1.97(1.81–2.16)
Pre-eclampsia
2.42(2.21–2.65)
Preexisting chronic hypertension
3.35(3.03–3.70)
- Women with incident DM during follow-up
- 16,670
Observational data: associations, not effects.
Further findings
Cumulative incidence of DM after pre-eclampsia, by concomitant gestational diabetes
%
- Pre-eclampsia with gestational diabetes
- 15.8
- Pre-eclampsia without gestational diabetes
- 1.8
Pre-eclampsia duration
- Pre-eclampsia duration significantly associated with higher risk of DM
Occurrence of HDP
%
- Pre-eclampsia
- 2.6
- Gestational hypertension (GH) alone
- 4.6
Original publication
Impact of different types of hypertensive disorders of pregnancy and their duration on incident post-partum risk of diabetes mellitus: Results from the French nationwide study CONCEPTION. Diabetes Metab. Published 25 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →