Gestational diabetes & diabetes in pregnancy

Physiological response during exercise is preserved in children exposed to a suboptimal gestational environment

Obesity (Silver Spring)Published Cohort study

Authors' conclusion

Children exposed to investigated SGFs display a similar physiological response regarding ME and substrate oxidation during rest and exercise compared to nonexposed children. Future studies should confirm these novel results and continue investigating other research avenues to explain the higher risk of obesity in this population.

Study context

Population
Children aged 8 to 10 years, Quebec Adiposity and Lifestyle Investigation in Youth cohort; incremental maximal cycling test with indirect calorimetry
Participants
68 / 49 / 77 / 370
Exposure
Children exposed to suboptimal gestational factors (SGFs) vs nonexposed children
  • GDMn = 68
  • Hypertensive disordersn = 49
  • Maternal smokingn = 77
  • Nonexposedn = 370reference
Outcome
Mechanical efficiency (ME) and substrate oxidation during rest and exercise

Main finding

As reported in the abstract

Mechanical efficiency (ME) during submaximal effort; no difference
F[3,540] 0.46; P = 0.713
ME during maximal effort; no difference
F[3,545] 0.86; P = 0.463
% contribution of lipids and carbohydrates at rest; did not differ
F[3,545] 1.68; P = 0.169
% contribution of lipids and carbohydrates during submaximal exercise; did not differ
F[3,544] 0.31; P = 0.534

Observational data: associations, not effects.

Original publication

Physiological response during exercise is preserved in children exposed to a suboptimal gestational environment. Obesity (Silver Spring). Published 24 July 2024. doi:10.1002/oby.24049

Composed by AI from the published abstract and checked against it. How Briefs are made →

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