Hyperandrogenism and Cardiometabolic Risk in Pre- and Postmenopausal Women—What Is the Evidence?
Authors' conclusion
To conclude, hyperandrogenism in premenopausal women is associated with enhanced prevalence of cardiovascular risk factors, as well as increased risk of cardiovascular disease and mortality, independently of body mass index. In contrast, elevated cardiovascular risk factors and increased risk of myocardial infarction and stroke in hyperandrogenic postmenopausal women are dependent on obesity. Furthermore, the overall risk of cardiovascular disease and coronary artery disease in hyperandrogenic postmenopausal women is similar to controls.
Study context
- Population
- Pre- and postmenopausal women with hyperandrogenism
- Outcome
- Cardiometabolic risk
Methodological detailsQuality of data overall low
- Quality of data overall low
Pooled result
As reported in the abstract
- Premenopausal: hyperandrogenism associated with higher prevalence of CV risk factors and increased risk of CVD and mortality, independent of BMI
- Postmenopausal: elevated CV risk factors and increased risk of MI and stroke dependent on obesity
- Postmenopausal: overall risk of CVD and coronary artery disease similar to controls
Original publication
Hyperandrogenism and Cardiometabolic Risk in Pre- and Postmenopausal Women—What Is the Evidence? J Clin Endocrinol Metab. Published 27 October 2023. doi:10.
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