Hormone Replacement Therapy after Pubertal Induction in Adolescents and Young Adults with Turner Syndrome: A Survey Study
Authors' conclusion
Although most endocrinologists and gynecologists report confidence in prescribing HRT to AYA with TS after pubertal induction, there are clear differences in provider preferences based on specialty and higher volume of patients with TS in their practice. Additional studies on comparative effectiveness of the HRT regimens and evidence-based guidelines are necessary for AYA with TS.
Study context
- Population
- Email listserv members of North American Society for Pediatric and Adolescent Gynecology (NASPAG) and the Pediatric Endocrine Society in North America; Hormone replacement therapy (HRT) preferences for primary ovarian insufficiency (POI) after completed pubertal induction in and young adults (AYA) with turner syndrome (TS)
- Participants
- 155 providers
- Exposure
- Gynecologists vs endocrinologists
- Outcome
- Current HRT practice patterns (preferred HRT) after pubertal induction in AYA with TS
Methodological details19-question survey, multinomial logistic regression
- 19-question survey
- Multinomial logistic regression
Main finding
As reported in the abstract
HRT practice patterns
- Reported confidence in prescribing HRT
- 87% (135)
- Aware of published guidelines
- 51%, 79
- Specialty associated with preferred HRT
- p = 0.032
- No. of patients with TS seen every 3 months associated with preferred HRT
- p = 0.024
Observational data: associations, not effects.
Original publication
Hormone Replacement Therapy after Pubertal Induction in Adolescents and Young Adults with Turner Syndrome: A Survey Study. Horm Res Paediatr. Published 24 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →