Hip fractures and type 2 diabetes in the elderly: Risk factors analysis of the Nedices cohort
Authors' conclusion
- RFs for hip fractures in T2D are similar to those in the general population. Osteoporosis, being female, and advancing age were independent RFs for hip fractures. There was an inverse association between educational level, community allocation, and physical activity which may further contribute to hip fracture risk. These highlights the need for research to better understand the role of T2D and these RFs in hip fracture incidence.
Study context
- Population
- Adults aged ≥65 years in three Spanish communities with different socioeconomic backgrounds (Nedices cohort)data from 5278 participants
- Participants
- 874 vs 4,494
- Exposure
- T2D vs controls
- T2Dn = 874
- Controlsn = 4,494reference
- Outcome
- Incidence of hip fractures
- Follow-up
- 3-year follow-up
Methodological detailspopulation-based, baseline and 3-year follow-up survey, three Spanish communities with different socioeconomic backgrounds
- Population-based
- Baseline and 3-year follow-up survey
- Three Spanish communities with different socioeconomic backgrounds
Main finding
As reported in the abstract
Incidence of T2D in individuals with vs without hip fractures
- The rate of incidence of T2D between individuals with and without fractures was not different
Observational data: associations, not effects.
Further findings
Baseline factors associated with hip fractures
- Body mass index (BMI) slightly higher in individuals with hip fractures
- Significant differences in BMI, education level, physical activity, osteoporosis, cataracts and osteoarthritis
Follow-up factors associated with hip fractures
- Compared: newly T2D, previously T2D and controls
- 96, 615, 2985
- Hip fractures associated with lower educational attainment, sedentary life and higher diagnoses of osteoporosis, cataracts and osteoarthritis
- Charlson index higher in individuals with hip fractures
- Higher proportion of fractures in urban areas
Original publication
Hip fractures and type 2 diabetes in the elderly: Risk factors analysis of the Nedices cohort. Diabetes Metab. Published 21 April 2025. doi:10.
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