Type 2 & other diabetes

Health effects associated with consumption of processed meat, sugar-sweetened beverages and trans fatty acids: a Burden of Proof study

Nat MedPublished Systematic review and meta-analysis

Authors' conclusion

These associations each received two-star ratings reflecting weak relationships or inconsistent input evidence

Study context

Population
Studies of processed meat, SSB and TFA consumption and T2D, ischemic heart disease and colorectal cancer
Comparison
Consumption of processed meat, sugar-sweetened beverages (SSBs) or trans fatty acids (TFAs) vs zero consumption
Outcome
Conservative average increase in risk relative to zero consumption
Methodological detailsBurden of Proof meta-regression, dose-response, conservative estimates relative to zero consumption
  • Burden of Proof meta-regression
  • Dose-response
  • Conservative estimates relative to zero consumption

Pooled result

As reported in the abstract

Processed meat (0.6-57 g d-1): T2D risk increase, at least
11%
Processed meat (0.78-55 g d-1): colorectal cancer risk increase, at least
7%
SSB intake (1.5-390 g d-1): T2D risk increase, at least
8%
SSB intake (0-365 g d-1): ischemic heart disease risk increase, at least
2%
TFA consumption (0.25-2.56% of daily energy intake): ischemic heart disease risk increase, at least
3%

Original publication

Health effects associated with consumption of processed meat, sugar-sweetened beverages and trans fatty acids: a Burden of Proof study. Nat Med. Published 30 June 2025. doi:10.1038/s41591-025-03775-8

Composed by AI from the published abstract and checked against it. How Briefs are made →

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