Glycemia Risk Index is Associated With Risk of Albuminuria Among Individuals With Type 1 Diabetes
Authors' conclusion
Glycemia risk index is significantly associated with albuminuria in individuals with type 1 diabetes.
Study context
- Population
- Individuals with T1D with 90-day continuous glucose monitoring (CGM) tracings; mean glycemia risk index (GRI) 40.9 ± 21.3, HbA1c 7.3 ± 1.0%
- Participants
- 330 individuals
- Exposure
- GRI zones (A–E) and its hypoglycemia and hyperglycemia components in relation to albuminuria
- Outcome
- Albuminuria (spot urine albumin-to-creatinine ratio ≥30 mg/g)
Main finding
As reported in the abstract
Albuminuria by GRI zone
- Adjusted OR of albuminuria per increase in GRI zone
- 1.70 (95% CI 1.19-2.41)
- Prevalence of albuminuria differed significantly by GRI zone
- P = .023
- Overall prevalence of albuminuria
- 17.6%
Observational data: associations, not effects.
Further findings
Albuminuria by hyperglycemia component of GRI
- Adjusted OR, also adjusted for HbA1c
- 1.44 (95% CI 1.05-1.98)
Original publication
Glycemia Risk Index is Associated With Risk of Albuminuria Among Individuals With Type 1 Diabetes. J Diabetes Sci Technol. Published 8 January 2025. doi:10.
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