Type 1 diabetes

The glycaemic response to morning fasted resistance exercise is more consistent than the response to afternoon fed resistance exercise for adults with type 1 diabetes: a randomised crossover comparison

DiabetologiaPublished Randomised crossover trial

Authors' conclusion

The glycaemic response to AM-FAST was more consistent and characterised by increases in glucose concentration, whereas the glycaemic response to PM-FED was less consistent and produced decreases in glucose concentration.

Study context

Population
Adults with T1D, HbA1c <85 mmol/mol (10.0%), aged 18–55 years, without contraindications to resistance exercise; University of Albertasix sessions each
Participants
12 adults
Comparison
Morning fasted vs afternoon fed resistance exercise
Primary endpoint
Within-participant SD (wpSD) of the capillary blood glucose response
Methodological detailsunblinded, supervised
  • Unblinded
  • Supervised

Primary result

As reported in the abstract

wpSD of change in capillary glucose during exercise

AM-FAST

1.0

± 1.1 · mmol/l

PM-FED

1.5

± 1.0 · mmol/l

P = 0.029

Further findings

OutcomeAM-FASTPM-FEDP value
Change in capillary glucose during exerciseIncrease for AM-FAST, decrease for PM-FED1.4 ± 1.9 mmol/l0.9 ± 2.3 mmol/lP = 0.017
% time in hyperglycaemia (CGM) · 6 h post exercise56.7% (interval 27.2–67.9)33.0% (interval 22.6–41.5)P = 0.003
Within-participant standard deviation (wpSD) during 30 min seated recovery · 30 min post exercise
P = 0.76

wpSD during 30 min seated recovery · 30 min post exercise

No difference in wpSD between conditions

Original publication

The glycaemic response to morning fasted resistance exercise is more consistent than the response to afternoon fed resistance exercise for adults with type 1 diabetes: a randomised crossover comparison. Diabetologia. Published 14 March 2026. doi:10.1007/s00125-026-06713-6

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