Glycaemic impact of the pre‐exercise timing of an elevated glucose target implemented using an automated insulin delivery system in adults with type 1 diabetes
Authors' conclusion
Glycaemia with exercise was excellent regardless of TT timing, which had no measurable effect on TBR during and post-exercise in a well-controlled cohort in the absence of a recent meal.
Study context
- Population
- Adults with T1D using the Medtronic MiniMed 780G automated insulin delivery (AID) system; 16 exercise bouts each (12 afternoon: 40 and 90 min MIE, 40 min HIE; 4 morning 40 min MIE)
- Participants
- 26 adults
- Comparison
- Temporary elevated glucose target set 20 min, 0 min or not set pre-exercise vs 60 min pre-exercise
- Primary endpoint
- TBR (<70 mg/dL)
- Follow-up
- Exercise commencement to 2 h post-exercise
Methodological detailswithin-participant comparison of 4 TT timing conditions, sign rank test vs TT60, Oral carbohydrate pre-exercise for glucose <100 mg/dL and during exercise for sensor glucose <70 mg/dL or confirmed symptomatic hypoglycaemia
- Within-participant comparison of 4 TT timing conditions
- Sign rank test vs TT60
- Oral carbohydrate pre-exercise for glucose <100 mg/dL and during exercise for sensor glucose <70 mg/dL or confirmed symptomatic hypoglycaemia
Primary result
As reported in the abstract
exercise commencement to 120 min post-exercise
Median time below range (TBR) for all conditions, with no difference between TT conditions
0%
Further findings
| Outcome | P value |
|---|---|
| Insulin delivery · 2 h pre-exerciseTTnil vs TT60 · higher with TTnil | P = 0.013 |
Starting glucose, time in range (TIR), participants with a hypoglycaemia episode · exercise commencement to 2 h post-exercise
- No difference between TT conditions
Original publication
Glycaemic impact of the pre‐exercise timing of an elevated glucose target implemented using an automated insulin delivery system in adults with type 1 diabetes. Diabetes Obes Metab. Published 25 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →