Little Loopers – a case series of automated insulin delivery usage with standard and diluted insulin in very young children with diabetes mellitus
Authors' conclusion
AID with both standard and diluted insulin can be used to safely manage diabetes in very young children with low total insulin requirements.
Study context
- Population
- Children aged <6 years with DM starting CamAPS FX automated insulin delivery (AID), single UK centre, October 2020–April 2022
- Participants
- 7 vs 4
- Exposure
- CamAPS FX AID with diluted vs standard insulin
- Dilutedn = 7
- Standardn = 4reference
- Outcome
- TIR (3.9-10.0 mmol/L)
- Follow-up
- Most recent clinic visit
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
Glucose variability · most recent clinic visit
Time from diagnosis to AID start
Time in hypoglycaemia (<3.9 mmol/L) · most recent clinic visit
- Median time in hypoglycaemia <4% in both groups
Safety
- Episodes of DKA or severe hypoglycaemia
- 0
Original publication
Little Loopers – a case series of automated insulin delivery usage with standard and diluted insulin in very young children with diabetes mellitus. Horm Res Paediatr. Published 23 June 2025. doi:10.
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