Diabetes technology

Continuous Glucose Monitoring–Guided Insulin Infusion in Critically Ill Patients Promotes Safety, Improves Time Efficiency, and Enhances Provider Satisfaction

Endocr PractPublished Retrospective cohort study

Authors' conclusion

Integrating rtCGM with an IICC protocol in the ICU enhances glycemic control, improves workflow efficiency, and reduces clinician workload while maintaining high accuracy.

Study context

Population
Critically ill adults requiring insulin infusion in surgical and medical intensive care unit (ICUs)
Participants
35 adults1,291 matched glucose pairs
Exposure
Real-time CGM (rtCGM) integrated into an insulin infusion computer calculator (IICC); CGM accuracy vs point-of-care (POC) glucose
  • rtCGM-IICCn = 35
Outcome
rtCGM accuracy vs POC glucose (1291 matched pairs)
Methodological detailssingle-group, surgical and medical ICUs
  • Single-group
  • Surgical and medical ICUs

Main finding

As reported in the abstract

Mean absolute relative difference (MARD) of rtCGM

12.5%

Values within clinically acceptable error zones (A+B), Parkes Error Grid

99.6%

Observational data: associations, not effects.

Further findings

OutcomeValues
CGM glycaemic metricsMean glucosertCGM-IICC mean 141.9 mg/dL · mean TIR (70-180 mg/dL) 82.8% · TAR (> 180 mg/dL) 14.5% · TBR (< 70 mg/dL) 0.5%

Clinician turnaround time for glucose monitoring

Clinician time efficiency improved significantly: POC testing mean turnaround nearly 5 minutes vs 3-second CGM retrieval

Nurse satisfaction

All surveyed nurses reported rtCGM increased efficiency and improved safety and preferred rtCGM with POC over POC alone
n = 20

Original publication

Continuous Glucose Monitoring–Guided Insulin Infusion in Critically Ill Patients Promotes Safety, Improves Time Efficiency, and Enhances Provider Satisfaction. Endocr Pract. Published 23 June 2025. doi:10.1016/j.eprac.2025.05.751

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