Diabetes technology

Accuracy and Glycemic Efficacy of Continuous Glucose Monitors in Critically Ill COVID-19 Patients: A Retrospective Study

J Diabetes Sci TechnolPublished Retrospective cohort study

Main finding · Glycemic control during IV insulin therapyResult — go to the resultMean difference −30.7 mg/dL

Authors' conclusion

Continuous glucose monitoring use in critically ill COVID-19 patients improved glycemic control during IV insulin therapy. Continuous glucose monitoring glucose data were highly concordant with POC glucose during IV insulin therapy in critically ill patients suggesting that CGM could substitute for POC measurements in inpatients thus reducing patient-provider contact and mitigating infection transmission.

Study context

Population
Critically ill patients with complications of COVID-19 requiring intravenous (IV) insulin
Participants
24 patients
Exposure
IV insulin periods with adjunctive continuous glucose monitoring (CGM) (Dexcom G6) vs without CGM; CGM accuracy vs point-of-care (POC) glucose
Outcome
Glycemic control during IV insulin therapy
Methodological detailsemergency use protocol, within-patient comparison of periods with and without adjunctive CGM, 47 333 CGM and 5677 POC glucose values
  • Emergency use protocol
  • Within-patient comparison of periods with and without adjunctive CGM
  • 47 333 CGM and 5677 POC glucose values

Main finding

As reported in the abstract

Mean difference

−30.7 mg/dL

Observational data: associations, not effects.

Further findings

CGM accuracy vs POC glucose (matched CGM:POC pairs)
14.8% · mean absolute relative difference · pairs in Clarke Error Grid Zones A and B 99.5%
CGM accuracy vs POC glucose (matched CGM:POC pairs) — Matched CGM:POC glucose pairs
2194

CGM accuracy vs POC glucose (matched CGM:POC pairs)

High degree of concordance between CGM and POC

Original publication

Accuracy and Glycemic Efficacy of Continuous Glucose Monitors in Critically Ill COVID-19 Patients: A Retrospective Study. J Diabetes Sci Technol. Published 25 July 2022. doi:10.1177/19322968221113865

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