Glycaemia Around Exercise in People With Type 1 Diabetes With and Without a Bolus Calculator: A Post Hoc Analysis of a Randomised Controlled Trial
Authors' conclusion
The use of an insulin bolus calculator implementing insulin reduction appeared to reduce the glucose decline during aerobic exercise, potentially reducing hypoglycaemia risk. However, increases in pre-exercise glucose indicate that a 50% reduction for moderate-intensity exercise may be excessive for some.
Study context
- Population
- Adults with T1D treated with MDI, completing 45 min of moderate-intensity cycling after breakfastcrossover
- Participants
- 17 adults
- Comparison
- Hedia Diabetes Assistant (HDA) bolus calculator app vs habitual diabetes management
- Primary endpoint
- Glucose rate of change (CGM), estimated by linear mixed-effects models
- Follow-up
- 1 h before to 1 h after exercise
Primary result
As reported in the abstract
Glucose rate of change, HDA vs control
Mean difference, mmol/L/min (95% CI)
HDAvs ControlPre-exercise; increase in glucose higher with HDA
0.043(0.023–0.062)
Between HDA and ControlDuring exercise; described as lower when using HDA
0.030(−0.003 to 0.063)
Between HDA and ControlPost-exercise; similar
0.002(−0.025 to 0.030)
Further findings
Glucose rate of change, all participants
mmol/L/min
- Before exercise (increase), 95% CI 0.030, 0.050
- 0.040
- During exercise (decline), 95% CI −0.058, −0.020
- −0.039
- Post-exercise (plateau), 95% CI −0.025, 0.030
- 0.002
Safety
Events
| Outcome | HDA | Control |
|---|---|---|
| Hypoglycaemic events | 0 | 2 |
Original publication
Glycaemia Around Exercise in People With Type 1 Diabetes With and Without a Bolus Calculator: A Post Hoc Analysis of a Randomised Controlled Trial. J Diabetes Sci Technol. Published 3 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →