Epidemiology of coeliac disease in children and adolescents with type 1 diabetes: a 13-year population-based study using secondary data sources
Main finding · CD prevalenceResult — go to the resultPrevalence ratio 18.6 95% CI 14.3–24.0Authors' conclusion
Children with T1D have a markedly increased risk of CD, particularly in the first years after diagnosis, supporting systematic CD screening in this high-risk population.
Study context
- Population
- Children aged <15 years, Marche Region, Central Italy, 2011–2023
- Exposure
- Children with T1D vs general paediatric population
- Outcome
- Prevalence and incidence of CD in the general paediatric population and among children with T1D
Methodological detailssecondary data sources (Healthcare Utilization Databases), 13-year
- Secondary data sources (Healthcare Utilization Databases)
- 13-year
Main finding
CD prevalence · 13-year period (2011-2023)
Prevalence ratio
18.6
95% CI 14.3–24.0
By group
T1D
97.7‰
T1Dvs General population
PR 18.6 (95% CI 14.3–24.0)
As reported in the abstract
- Overall Coeliac Disease (CD) period prevalence, children aged <15
- 5.28‰
Observational data: associations, not effects.
Further findings
| Outcome | T1D | General population | IRR (95% CI) | |
|---|---|---|---|---|
| CD incidence | 2,410 per 100,000 person-years | 65 per 100,000 person-years | 37.0 (24.7–55.4) | |
| 0.050.21520Incidence rate ratio (log scale) |
- Cumulative probability of developing CD in T1D cohort · 6 years
- 10.3% · CI 6.2%–14.3%
- CD incidence: T1D: newly diagnosed
T1D prevalence · 13-year period
- Overall prevalence of T1D
- 1.65‰
Original publication
Epidemiology of coeliac disease in children and adolescents with type 1 diabetes: a 13-year population-based study using secondary data sources. Diabetes Res Clin Pract. Published 2 April 2026. doi:10.
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