Glucose-Derived Personalized HbA1c Correction (GDAC) Study to Improve Alignment Between CGM-Derived Metrics and HbA1c in Different Individuals and Racial Groups With Diabetes: Implications for Clinical Practice
Authors' conclusion
HbA1c-AG discordance is common, particularly in the Black population, with pA1C improving alignment with glucose levels
Study context
- Population
- Individuals with T1D or T2D across four racial groups (35% Asian, 30% White, 22% Black, 14% other/mixed); mean age 53 ± 14 years, 45% females19% T1D
- Participants
- 257 individuals
- Exposure
- Personalized HbA1c vs HbA1c alignment with average glucose
- Outcome
- Clinically meaningful HbA1c-AG discordance of ≥0.5%
- Follow-up
- Weeks 20-26
Methodological details26-week, four racial groups
- 26-week
- Four racial groups
Main finding
≥0.5% HbA1c-AG discordance, whole population
Reduction
58%
By group
As reported in the abstract
Observational data: associations, not effects.
Further findings
≥0.5% HbA1c-AG discordance, Black population
reduction 71%
Original publication
Glucose-Derived Personalized HbA1c Correction (GDAC) Study to Improve Alignment Between CGM-Derived Metrics and HbA1c in Different Individuals and Racial Groups With Diabetes: Implications for Clinical Practice. Diabetes Care. Published 8 June 2026. doi:10. 2337/ dc26-0398
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