Diabetes technology

Glucose-Derived Personalized HbA1c Correction (GDAC) Study to Improve Alignment Between CGM-Derived Metrics and HbA1c in Different Individuals and Racial Groups With Diabetes: Implications for Clinical Practice

Diabetes CarePublished Prospective cohort study

Authors' conclusion

HbA1c-AG discordance is common, particularly in the Black population, with pA1C improving alignment with glucose levels

Study context

Population
Individuals with T1D or T2D across four racial groups (35% Asian, 30% White, 22% Black, 14% other/mixed); mean age 53 ± 14 years, 45% females19% T1D
Participants
257 individuals
Exposure
Personalized HbA1c vs HbA1c alignment with average glucose
Outcome
Clinically meaningful HbA1c-AG discordance of ≥0.5%
Follow-up
Weeks 20-26
Methodological details26-week, four racial groups
  • 26-week
  • Four racial groups

Main finding

≥0.5% HbA1c-AG discordance, whole population

Reduction

58%

By group

As reported in the abstract

Observational data: associations, not effects.

Further findings

≥0.5% HbA1c-AG discordance, Black population

reduction 71%

Original publication

Glucose-Derived Personalized HbA1c Correction (GDAC) Study to Improve Alignment Between CGM-Derived Metrics and HbA1c in Different Individuals and Racial Groups With Diabetes: Implications for Clinical Practice. Diabetes Care. Published 8 June 2026. doi:10.2337/dc26-0398

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