Continuous Glucose Monitoring–Derived Glucose Metrics Over Time in Physically Active Adults Without Diabetes Using a Commercial Continuous Glucose Monitoring Application
Authors' conclusion
These findings indicate both cumulative and day-to-day gains in glucose control with repeated sensor use for individuals with a TITR <95%. Indeed, CGM use coincided with short-term improvements in glucose metrics. Future studies should directly measure lifestyle behaviors to determine which factors may contribute to improvements in glycemia.
Study context
- Population
- Healthy, physically active adults without diabetes with mild dysglycemia (suboptimal time in tight range (TITR) <95%) wearing a real-time continuous glucose monitoring (CGM) (GSB) with a smartphone app for ≈8 weeks (4 wear periods); 51 females, 174 males, age 45.0 ± 10.1 years, BMI 23.4 ± 3.9 kg/m²
- Participants
- 225 participants
- Outcome
- Cumulative time in glycemic zones: TBR (<70 mg/dL), TITR (70-140 mg/dL), TAR (>140 mg/dL), across GSB wear periods (linear mixed-effects models)
- Follow-up
- Approximately eight weeks
Main finding
As reported in the abstract
Change in glycemic zones per day of sensor wear
TITR increase per day of sensor wear
0.59%
95% CI 0.50, 0.69P < 0.001
TBR change per day of sensor wear
−0.42 %
95% CI −0.50, −0.35P <.001
TAR change per day of sensor wear
−0.17 %
95% CI −0.24, −0.10P < .001
Observational data: associations, not effects.
Original publication
Continuous Glucose Monitoring–Derived Glucose Metrics Over Time in Physically Active Adults Without Diabetes Using a Commercial Continuous Glucose Monitoring Application. J Diabetes Sci Technol. Published 3 March 2026. doi:10.
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