Obesity

Genetic variant rs9939609 in FTO is associated with body composition and obesity risk in Korean females

BMJ Open Diabetes Res CarePublished Observational genetic association study

Main finding · Obesity risk (females)Result — go to the resultFold higher risk 1.28 95% CI 1.088–1.507

Authors' conclusion

The FTO rs9939609 variant is associated with body composition in Koreans, especially body fat markers in females. These results support that the FTO rs9939609 variant is a genetic risk factor in the etiology of obesity.

Study context

Population
Koreans from the Korean Genome and Epidemiology Study
Participants
6,474 participants
Exposure
FTO rs9939609 A allele carriers vs TT genotype
Outcome
Obesity and body composition markers
Methodological detailssex-stratified analysis
  • Sex-stratified analysis

Main finding

Obesity risk (females)

Fold higher risk

1.28

95% CI 1.088–1.507

As reported in the abstract

Observational data: associations, not effects.

Original publication

Genetic variant rs9939609 in FTO is associated with body composition and obesity risk in Korean females. BMJ Open Diabetes Res Care. Published 22 November 2023. doi:10.1136/bmjdrc-2023-003649

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