Fracture risk revisited: Bone mineral density T‐score and fracture risk in type 2 diabetes
Authors' conclusion
The FN BMD T-score was significantly associated with hip, non-spine and major osteoporotic fracture risk in men and women with and without T2D. Fracture risk for a given T-score and age was equal in individuals with and without T2D, as was the ability of the FN BMD T-score to predict fracture risk.
Study context
- Population
- Women and men with femoral neck (FN) bone mineral density (BMD) measured by DXA, Danish National Health Service35,129 women · 7069 men
- Exposure
- FN BMD T-score and fracture risk, with vs without T2D
- Outcome
- Association between FN BMD T-score and fracture risk (any, hip, major osteoporotic fracture)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
aHR, hip fracture, men with T2D
1.55
95% CI 1.01–2.36; IR 4.6
aHR, hip fracture, women without T2D
1.75
95% CI 1.64–1.87; IR 7.0
aHR, hip fracture, men without T2D
1.97
95% CI 1.73–2.25; IR 6.3
Observational data: associations, not effects.
Further findings
- Fracture incidence rate (IRs) not significantly different with vs without T2D, nor the estimated cumulative 10-year fracture risk
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →